Method details
Accurate Lumen Segmentation and Stenosis
Detection and Quanti cation in Coronary CTA
Abstract:
Accurate detection and quanti cation of coronary artery stenoses is fundamental in correct patient diagnosis and optimal treatment planning. Central to detection and quanti cation is the correct estimation of lumen in the coronary vessel.
Here, we describe a method for accurate lumen segmentation in CTA and present results of an early prototype for stenosis detection and quanti cation for a variety of datasets. For the detection, a sensitivity of 72% and a PPV of 17% is obtained as compared
to QCA, while a sensitivity of 57% and a PPV of 18% is achieved as compared to CTA. The stenosis degree is estimated with an absolute average di erence of 49% as compared to QCA, and a weighted kappa
value of -0.15 is obtained as compared to CTA. A Dice of 73% and 69% is
reported for lumen segmentation of healthy and diseased vessel segments
respectively.
Detection confusion tables
| Calc. cat. | QCA (per segment) | CTA (per lesion) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| TP | FP | FN | TP+FP | TP+FN | TP | FP | FN | TP+FP | TP+FN | |
| All | 16 | 95 | 12 | 111 | 28 | 24 | 129 | 23 | 153 | 47 |
The results of this method are based on the following centerlines: Rcadia team auto.
Detection (QCA per segment / CTA per lesion)
| Calc. cat. | QCA Sens. | QCA P.P.V. | CTA Sens. | CTA P.P.V. | Avg. rank | ||||
|---|---|---|---|---|---|---|---|---|---|
| % | rank | % | rank | % | rank | % | rank | ||
| 0 (0 - 0.1) | 80.0 | 1.0 | 16.0 | 9.0 | 71.4 | 3.0 | 13.9 | 12.0 | 6.2 |
| 1 (0.1 - 10) | 100.0 | 1.0 | 7.1 | 13.0 | 60.0 | 6.0 | 15.8 | 11.0 | 7.8 |
| 2 (11 - 100) | 71.4 | 4.0 | 17.2 | 12.0 | 54.5 | 8.0 | 14.3 | 12.0 | 9.0 |
| 3 (101 - 400) | 60.0 | 8.0 | 20.0 | 11.0 | 47.4 | 9.0 | 22.0 | 10.0 | 9.5 |
| 4 (400+) | 0.0 | 19.0 | 0.0 | 19.0 | 20.0 | 17.0 | 6.7 | 17.0 | 18.0 |
| All | 57.1 | 7.0 | 14.4 | 13.0 | 51.1 | 7.0 | 15.7 | 13.0 | 10.0 |
| For ranking | 57.1 | 7.0 | 14.4 | 13.0 | 51.1 | 7.0 | 15.7 | 13.0 | 10.0 |
These results are based on 30 datasets and 19 submissions.
Quantification
| Calc. cat. | QCA Avg. Abs. diff. | QCA R.M.S. diff. | CTA Weigthed Kappa | Avg. rank | |||
|---|---|---|---|---|---|---|---|
| % | rank | % | rank | Κ | rank | ||
| 0 (0 - 0.1) | 45.4 | 11.0 | 53.0 | 13.0 | 0.12 | 12.0 | 12.0 |
| 1 (0.1 - 10) | 47.5 | 13.0 | 54.0 | 14.0 | 0.16 | 11.0 | 12.2 |
| 2 (11 - 100) | 49.0 | 12.0 | 54.5 | 12.0 | 0.13 | 11.0 | 11.5 |
| 3 (101 - 400) | 48.9 | 12.0 | 55.1 | 12.0 | 0.18 | 11.0 | 11.5 |
| 4 (400+) | 66.7 | 14.0 | 70.7 | 14.0 | 0.23 | 12.0 | 13.0 |
| All | 49.6 | 12.0 | 56.0 | 15.0 | 0.15 | 12.0 | 12.8 |
| For ranking | 49.6 | 12.0 | 56.0 | 15.0 | 0.15 | 12.0 | 12.8 |